The abuse of controlled substances in the US and even world-wide has reached epidemic proportions. Significant administrative and technical resources are currently being expended to identify and implement technologies which deter, inhibit or prevent the unintentional, illicit, illegal and/or recreational use of controlled substances. While the origin of abuse may be accredited to the irresponsible behavior of the abuser, the detrimental effects to society remain.
The pharmaceutical industry has responded to this difficult problem in an attempt to provide controlled substance drug products possessing abuse deterrent features. Approaches such as through a prodrug, an intractable matrix formulation technique or by antagonist incorporation into a product have had only limited success.
National Institute on Drug Abuse
US Dept of Health & Human Services Alcohol and Drug Information